INTRODUCTION Print Section Listen Sickle-cell disease (SCD) is the most prevalent single-gene disorder, affecting about 100,000 Americans. Sickle-cell disease is a debilitating condition associated with chronic anemia, stroke, splenic and…
INTRODUCTION Print Section Listen Understanding of fibromyalgia syndrome (FMS) has evolved over the past 20 years. Once thought to be related to muscular pain and inflammation, it is now more…
INTRODUCTION Print Section Listen The basic principles of the diagnosis and management of pain syndromes are similar across all clinical settings. Details of the application of these principles, however, can…
INTRODUCTION Print Section Listen The prognosis of cancer in children has improved dramatically over the past 40 years. Unlike many adult cancers, pediatric malignancies are often responsive to initial aggressive…
OVERVIEW Print Section Listen Pain is a complex symptom experienced by many cancer patients. It affects most aspects of life, and controlling it well can make a great difference in…
INTRODUCTION Print Section Listen The understanding of postoperative pain has evolved greatly during the past half century. Many laboratory investigations have established that peripheral tissue injury during surgery can trigger…
INTRODUCTION Print Section Listen The development of debilitating central neuropathic pain (CNP), defined as pain caused by a lesion or dysfunction of the central nervous system (CNS),1,2 can occur after…
INTRODUCTION Print Section Listen Shingles is caused by the varicella-zoster virus (VZV), which primarily affects the dorsal root ganglia (DRG) of the spinal nerves or trigeminal nerve. A single DRG…
INTRODUCTION Print Section Listen Pain relief in an acute pain situation, besides having a humane value, has an important bearing in the well-being of an individual. Although it may not…
INTRODUCTION Print Section Listen Chronic, nonmalignant pain syndromes of the perineal area have been well described in the medical literature dating back more than 100 years. However, the etiology of…
