There are a number of dangerous secondary causes of headaches that are life, limb, brain, or vision threatening that emergency physicians must consider in patients presenting with acute headache. Careful…

Jonathan A. Edlow, MD, Editor Michael K. Abraham, MD, MS, Editor When Dr Amal Mattu asked us to consider organizing and editing this issue of Emergency Medicine Clinics of North…

Amal Mattu, MD, FAAEM, FACEP, Consulting Editor If you were to ask emergency physicians which organ system they feel least comfortable managing in times of emergency, the majority are likely…

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA www.emed.theclinics.com Consulting Editor AMAL MATTU November 2016 • Volume 34 • Number 4

SEP-1, the new national quality measure on sepsis, resulted from an undertaking to standardize care for severe sepsis and septic shock regardless of the size of the emergency department where…

Sepsis represents a unique clinical dilemma with regard to antimicrobial stewardship. The standard approach to suspected sepsis in the emergency department centers on fluid resuscitation and timely broad-spectrum antimicrobials. The…

Sepsis is a challenging, dynamic, pathophysiology requiring expertise in diagnosis and management. Controversy exists as to the most sensitive early indicators of sepsis and sepsis severity. Patients presenting to the…

Prehospital care providers are tasked with the delivery of time-sensitive care, and emergency medical services (EMS) systems must match patients to appropriate clinical resources. Modern systems are uniquely positioned to…

Our evolving understanding of the physiologic processes that lead to sepsis has led to updated consensus guidelines outlining priorities in the recognition and treatment of septic patients. However, an enormous…

Sepsis is recognized by the presence of physiologic and laboratory changes that reflect the inflammatory response to infection on cellular and systemic levels. Comorbid conditions, such as cirrhosis, end-stage renal…