Beware of Metabolites
Beware of Metabolites Bradford D. Winters MD, PHD Many drugs are metabolized to active metabolites. This is usually carried out by the liver in the form of reductions, oxidations, and…
Beware of Metabolites Bradford D. Winters MD, PHD Many drugs are metabolized to active metabolites. This is usually carried out by the liver in the form of reductions, oxidations, and…
Use Prophylaxis for Erosive Gastritis in the Appropriate Patient Rachel Bluebond-Langner MD Gastrointestinal (GI) prophylaxis in the intensive care unit (ICU) is important in the prevention of stress gastritis. The…
Strongly Consider Starting an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker after Myocardial Infarction Ying Wei Lum MD The renin-angiotensin-aldosterone system (RAAS) regulates aldosterone release in the body via the…
Be Aggressive in Considering Reperfusion Therapy in Acute Myocardial Infarction Anthony D. Slonim MD, DrPH Cardiovascular disease is a dominant cause of morbidity and mortality in the United States and…
Consider Nesiritide in Acutely Decompensated Heart Failure Jacqueline Janka MD In patients with cardiogenic pulmonary edema due to acute decompensated heart failure, plasma brain natriuretic peptide (BNP) measurements can guide…
Strongly Consider Using Glycoprotein IIb/IIIa Inhibitors as an Added Treatment to Stenting in Acute Myocardial Infarction Nirav G. Shah MD Percutaneous coronary intervention (PCI) with stenting has revolutionized the care…
Strongly Consider Low-Molecular-Weight Heparin in the Treatment of Unstable Angina and Non-ST-Elevation Myocardial Infarction Julius Cuong Pham MD Case Mrs. ACS is a 74-year-old female who is admitted to the…
Consider the Use of Glycoprotein IIb/IIIa Inhibitors in Unstable Coronary Syndromes Andrew L. Rosenberg MD Current treatments for acute coronary syndromes including unstable angina and non-ST-elevation myocardial infarction now include…
Consider Thrombolytics in ST-Elevation Myocardial Infarction if Percutaneous Coronary Intervention is not Available or Delayed Julius Cuong Pham MD Case Mr. AMI is a 66-year-old male who is postoperative day…
Remember that Cardiac Pressors do not Work in a Low-pH Environment Bradford D. Winters MD, PhD Critically ill patients often require inotropic and/or pressor support to maintain adequate cardiac output…