Remember that Activated Protein C is not as Useful for Sepsis as Once Hoped Ronald W. Pauldine MD Activated protein C (APC) exerts a number of biological effects including anti-inflammatory,…
Try to Avoid Using Benzodiazepines for Sleep in the Intensive Care Unit, Especially in the Elderly Bryan A. Cotton MD During hospitalization, repeated arousals disrupt sleep continuity. These awakenings are…
Do not use Midazolam and Lorazepam Interchangeably in the Intensive Care Unit M. Craig Barrett PharmD Ronald F. Sing DO A common misconception regarding benzodiazepines used in the intensive care…
Look for Medication-Induced Causes of Hyperglycemia in Intensive Care Patients Edward T. Horn PharmD Hyperglycemia, defined as blood glucose levels >110 mg/dL, has been shown in multiple studies to adversely…
Remember that Patients with Insulin Deficiency Require Basal Insulin Even When They Are Nil Per Os Kathleen A. Williams RN, MSN CRNP Sherita Hill Golden MD, MHS Maintaining euglycemia (defined…
Do not use Insulin Glargine in the Intensive Care Unit Without Also Giving A Shorter-Acting Insulin Form Kristin Shipman MD Heidi L. Frankel MD Lantus is a long-acting insulin analogue…
Do not use Subcutaneous Insulin in the Intensive Care Unit Population Kristin Shipman MD Heidi L. Frankel MD Regular insulin should be administered intravenously and not subcutaneously in the intensive…
Maintain Tight Glucose Control in the Intensive Care Unit Michael J. Moritz MD Hyperglycemia and insulin resistance are common in critically ill patients even if they did not have diabetes…
Consider use of Enoxaparin over Unfractionated Heparin in Trauma Patients Suneel Khetarpal MD Barbara Haas MD Trauma patients are at high risk of deep venous thromboembolism, with the majority of…
Do not use Erythromycin as a Prokinetic Agent in Patients on Tacrolimus (Or Cyclosporine) Matthew J. Weiss MD Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis and is…
