Psychotherapeutic Drugs

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Psychotherapeutic Drugs

HIGH-YIELD FACTS Print Section Listen The key targets of antidepressant and neuroleptic poisoning are the cardiovascular and central nervous systems (CNS). Tricyclic antidepressant (TCA) poisoning is potentially life-threatening due to…

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Thyroid Hormones

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Thyroid Hormones

HIGH-YIELD FACTS Print Section Listen Acute ingestions are generally benign but may be delayed in onset (2–4 days). Ingestions of greater than 5 mg warrant measurement of T4 concentration at…

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Acetaminophen

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Acetaminophen

HIGH-YIELD FACTS Print Section Listen Widely available in both prescription and OTC products, acetaminophen is a common pediatric overdose. Acetylcysteine is the antidote for acetaminophen overdose and can be given…

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Iron Poisoning

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Iron Poisoning

HIGH-YIELD FACTS Print Section Listen Estimation of risk of iron poisoning is based upon conversion of the ingested iron salt to elemental iron with >60 mg/kg being associated with significant…

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Cardiovascular Drugs

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Cardiovascular Drugs

HIGH-YIELD FACTS Print Section Listen β-Blocker and calcium channel blocker poisoning have significant morbidity, and their hallmark is bradycardia and hypotension. If standard Pediatric Advance Life Support (PALS) protocols do…

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Sedative Hypnotics and Anticonvulsants

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Sedative Hypnotics and Anticonvulsants

HIGH-YIELD FACTS Print Section Listen The hallmark of the care of children with sedative hypnotic poisoning is meticulous supportive care with particular attention to the support of airway and breathing….

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Opioids

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Opioids

HIGH-YIELD FACTS Print Section Listen Opioid toxicity is characterized by the classic triad of central nervous system depression, respiratory depression, and miosis. Some opioids, such as methadone, can have prolonged…

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Nonsteroidal Anti-Inflammatory Drugs

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Nonsteroidal Anti-Inflammatory Drugs

HIGH-YIELD FACTS Print Section Listen Nonsteroidal anti-Inflammatory drugs (NSAIDs) are relatively devoid of toxicity in the overdose setting. Patients who develop toxicity exhibit central nervous system or gastrointestinal signs and…

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Aspirin

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on Aspirin

HIGH-YIELD FACTS Print Section Listen Salicylate poisoning is difficult to treat, and consultation with a medical toxicologist is recommended. Children with aspirin toxicity can rapidly develop metabolic acidosis without an…

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General Approach to the Poisoned Patient

Jan 9, 2019 by in EMERGENCY MEDICINE Comments Off on General Approach to the Poisoned Patient

HIGH-YIELD FACTS Print Section Listen The cardinal principle of the management of the poisoned patient is meticulous supportive care. Gastrointestinal decontamination plays a limited role in the routine management of…

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