Thrombolytic Therapy: Evidence-Based Results from Multicenter Control Trials
Years Author Number of patients 1970–2000 UPETSG (1970) 160 Tibbutt et al. (1974) 30 Ly et al. (1978) 25 Marini et al. (1988) 30 Levine et al. (1990) 58 PIOPED…
Current Guidelines and Recommendations for Thrombolysis Use in Pulmonary Embolism
Level A: Multiple populations evaluated. Data derived from multiple randomized clinical trials or meta-analyses Level B: Limited populations evaluated. Data derived from a single randomized trial or nonrandomized studies Level…
Thrombolysis in Pulmonary Embolism
Fig. 7.1 Modified of C Jerjes Sanchez y cols. Ischemic cascade that are generated from a massive PE over the right ventricle, and the phenomena that can increase or reduce…
Supranormal Elevation of Systemic Oxygen Delivery in Critically Ill Patients
Intervention Indications Cautions Side effects Protocol Notes Supranormal elevation of oxygen delivery Critically ill patients at increased risk of death Patients not responding to initial challenge have a worse prognosis…
Is Therapeutic Hypothermia Beneficial for Out-of-Hospital Cardiac Arrest?
1st author/year N Durationof study Participants Therapeutic intervention Control intervention Follow-up time Conclusion HACA/2002 [5] 275 65 m Unconscious OHCA patients, cardiac cause of arrest (initial rhythm VF or non-perfusing…
Reducing Mortality in Critically Ill Patients: A Systematic Update
Inclusion criteria 1. Published in peer-reviewed journal 2. Multicenter randomized design 3. Dealt with a nonsurgical intervention (drug/technique/strategy) 4. Involving adult critically ill patients 5. Showing a statistically significant reduction…
Glutamine Supplementation in Critically Ill Patients
Drug Indications Contraindications Side effects Dose Note Glutamine (alanyl-glutamine and glycine-glutamine) Critically ill patients (intensive care unit patients, burns, surgical patients) Bone marrow transplant Weight loss in patients with AIDS…
High-Frequency Oscillatory Ventilation
Technique Indications Contraindications Side effects Protocol Note High-frequency oscillatory ventilation (HFOV) Acute respiratory distress syndrome with hypoxemia refractory to conventional protective ventilation Recent lung surgery, lung disease characterized by airway…
Does β2-Agonist Use Improve Survival in Critically Ill Patients with Acute Respiratory Distress Syndrome?
Fig. 13.1 Schematic diagram showing the scientific rationale and potential role of β2-agonists in ARDS (Adopted from: Bassford et al. [13]. Permission to reproduce granted under BioMed Central’s general terms)…
Diaspirin Cross-Linked Hemoglobin and Blood Substitutes
Always available without temperature limitations Long shelf life Effective oxygen-carrying capacity Effective volume expander Absent scavenging effect on nitric oxide No side effects No infectious carrier No crossmatching necessity Cost-effective…
