Chapter 28 – Cardiac Cycle

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Abstract The cardiac cycle refers to the complete sequence of physiological events that occur in the heart, from the beginning of one heartbeat to the beginning of the next. Chapter…

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Chapter 27 – Cardiac Anatomy and Function

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Abstract The right side of the heart generates flow around the pulmonary circulation, moving deoxygenated venous blood from the heart to the lungs. Chapter 27 Cardiac Anatomy and Function What…

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Chapter 23 – Pulmonary Circulation

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Abstract The pulmonary circulation differs significantly in characteristics from the systemic circulation. The pulmonary circulation is a low-pressure, low-resistance, high-flow circulation: a blood flow of 5 L/min (i.e. 100% of…

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Chapter 21 – Work of Breathing

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Abstract The work of breathing is the energy consumed by the respiratory muscles throughout the respiratory cycle. Chapter 21 Work of Breathing What is meant by the term ‘work of…

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Chapter 26 – Anaesthesia and the Lung

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Abstract Many of the drugs used by anaesthetists have effects on the medullary respiratory centre, the peripheral chemoreceptors and the airways. Their effects are most easily classified by drug class….

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Chapter 25 – Ventilatory Failure

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Abstract Respiratory failure occurs when the respiratory system fails in one or both of its main functions; namely, the oxygenation of blood and the elimination of CO2. Respiratory failure is…

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Chapter 24 – Oxygen Toxicity

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Abstract The central nervous system (CNS), causing seizures and unconsciousness when breathing hyperbaric O2, which is of obvious importance for divers. CNS toxicity is known as the Paul Bert effect….

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Chapter 22 – Control of Ventilation

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Abstract Sensors – the central and peripheral chemoreceptors, pulmonary stretch receptors, J-receptors, irritant receptors and joint proprioceptors. Chapter 22 Control of Ventilation Which anatomical sites are involved in the control…

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Chapter 20 – Lung Compliance

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Abstract Compliance is defined as the change in lung volume produced by a unit change in transpulmonary pressure. Lung compliance is represented by the gradient of the pressure–volume curve. Chapter…

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Chapter 19 – Oxygen Cascade

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Abstract The O2 cascade concept draws together areas of respiratory physiology covered in the previous few chapters. In an examination setting, it allows the examiner to assess your knowledge of…

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