Abstract The ability of the human body to maintain normothermia via physiological reactions or behavioural changes to vastly different climatic circumstances is an evolutionarily well preserved mechanism. It is a…

Abstract With the advances in computational technology, artificial intelligence (AI) systems have been growing exponentially and promise to become tools that are able to overcome some of the most difficult…

Abstract Even though practices do differ geographically, general anaesthesia often involves some mode of mechanical ventilation different from normal spontaneous ventilation. This chapter will focus on the differences between these…

Abstract Liver surgery can be remarkably safe: a zero mortality rate has been achieved with liver resections when patients are properly selected and with meticulous perioperative care [1]. In order…

Abstract In Europe, approximately 30% of surgeries are performed in patients with cardiovascular comorbidities and up to 42% of intraoperative complications are cardiac related [4]. Often, the anaesthesiologist needs to…

Abstract Respiratory depression is a common and unwanted side-effect of anaesthetics, sedatives and analgesics. It has been known since the end of the 18th century that anaesthesia has pronounced effects…

Abstract Surgical anaesthesia usually requires hypnosis, antinociception (ensuring blood pressure and heart rate control) and immobility with varying degrees of muscle relaxation. However, the relative contribution of these three components…

Abstract The ageing population in Western countries combined with advances in anaesthetic management and surgical techniques results in a growing number of frail patients presenting for surgery in the last…

Abstract Surgery and anaesthesia alter the function of the brain and its control mechanisms. In the operating room, we daily observe the effects of anaesthetic agents during induction and recovery…