Anticonvulsant Poisoning
Anticonvulsant Poisoning Steven B. Bird Anticonvulsants can be divided into four groups based on their primary mechanism of action: those that primarily act on neuronal membranes (membrane-active agents), those that…
Anticholinergic Poisoning†
Anticholinergic Poisoning† Keith K. Burkhart The classic anticholinergic syndrome manifests an easily recognizable toxidrome, but patients may present with some but not all of the classic symptoms. Decreased secretions, tachycardia,…
Antiarrhythmic Agents
Antiarrhythmic Agents Michael Ganetsky The therapeutic use, misuse, and intentional overdose of antiarrhythmic drugs are associated with severe morbidity and mortality [1]. The recognition, management, and prevention of antiarrhythmic toxicity…
Alcohols and Glycol Poisoning
Alcohols and Glycol Poisoning Jennifer L. Englund Marco L.A. Sivilotti Marsha D. Ford The accidental or deliberate consumption of alcohols and glycols is a major cause of health problems [1,2]….
Acetaminophen Poisoning
Acetaminophen Poisoning Steven B. Bird Pharmacology Acetaminophen (N-acetyl-para-aminophenol [APAP]) is a nonnarcotic analgesic with excellent antipyretic activity but almost no anti-inflammatory effects. It belongs to the same drug family as…
General Considerations in the Evaluation and Treatment of Poisoning
General Considerations in the Evaluation and Treatment of Poisoning Ian M. Ball Christopher H. Linden The objective of this chapter is to provide the general intensivist with both an overview…
Oncologic Emergencies
Oncologic Emergencies Damian J. Green John A. Thompson Bruce Montgomery The clinical presentation of oncologic emergencies has not changed dramatically over the past 50 years; however, the efficacy and variety…
Transfusion Therapy: Blood Components and Transfusion Complications
Transfusion Therapy: Blood Components and Transfusion Complications Terry Gernsheimer Transfusion support can be a key element in decreasing morbidity and mortality of the critically ill patient by the support of…
Critical Care of Patients with Hematologic Malignancies
Critical Care of Patients with Hematologic Malignancies Matthew J. Wieduwilt Lloyd E. Damon Introduction Although the incidence of aggressive hematologic malignancies like acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL),…
Anemia in the Critical Care Setting
Anemia in the Critical Care Setting Marc S. Zumberg Marc J. Kahn Alice D. MA General Principles Anemia is common in the critical care setting. Recent studies have shown that…
