The Failure of DO 2– Did What I Do to the Patient Just Work?
By now, I wouldn’t be surprised if you were asking yourself, “I thought this was a book about ECMO?” Why are we talking about hemoglobin dissociation, shock recognition, shunt physiology,…
Recognition of Shock
Now we are going to bring our discussion of shock to the next level and start to explore some patterns that can help us with recognition of shock. Remember, if…
Displacement of intervertebral discs
Key points • Intervertebral disc displacement is not a “disease,” but is a component of many variations of disorders of the spine. • The displaced disc material and the effects…
Anatomy of the spine
Key points • Intimate relationships between osseous, nervous, vascular, and soft tissue structures of the spine are critical to normal function. • A thorough understanding of these relationships is essential…
Disc space narrowing and osteophytes
Key points • Disc space narrowing and osteophyte formation are features of the general spine condition known as intervertebral disc (IVD) degeneration • IVD degeneration is an age-related condition •…
Imaging technologies of the spinal discs
Key points • Various imaging modalities exist to assess the intervertebral disc. • Classification grading schemes have been proposed to assess the morphological and structural changes of the disc. •…
Intervertebral disc degeneration
Key points • The process of intervertebral disc (IVD) degeneration consists of gradual structural and biochemical changes that may lead to pain and disability. • IVD degeneration is multifaceted, mediated…
Biomechanical models to study spinal phenotypes
Key points • Intervertebral disc (IVD) degeneration involves endplate-driven and annulus-driven phenotypes that accumulate and interact with progressive degeneration and eventual collapse of the IVD. • IVD injuries result in…
