Malignant Hyperthermia
Chapter 124 Malignant Hyperthermia Barbara W. Brandom, Mihaela Visoiu Pearls • Malignant hyperthermia (MH) is a muscle disorder first recognized as a complication of general anesthesia with the potent inhalational…
Neuromuscular Blocking Agents
Chapter 122 Neuromuscular Blocking Agents Joseph D. Tobias Pearls • As neuromuscular blocking agents (NMBAs) result in blockade of skeletal muscle function, these agents cause cessation of ventilatory function, mandating…
Pediatric Renal Replacement Therapy in the Intensive Care Unit
Chapter 72 Pediatric Renal Replacement Therapy in the Intensive Care Unit Jordan M. Symons, Stuart L. Goldstein Pearls • Patients receiving renal replacement therapy require careful monitoring of fluid and…
Glomerulotubular Dysfunction and Acute Kidney Injury
Chapter 71 Glomerulotubular Dysfunction and Acute Kidney Injury Surender Rajasekaran, Norma J. Maxvold, Timothy E. Bunchman Pearls • Acute kidney injury (AKI) has replaced the term acute kidney failure. There…
Thoracic Injuries in Children
Chapter 114 Thoracic Injuries in Children Mauricio A. Escobar, Jr., Michael G. Caty Pearls • Thoracic injuries in children are uncommon but result in significant morbidity and mortality, mainly from…
Research in Pediatric Critical Care
Chapter 4 Research in Pediatric Critical Care Randall C. Wetzel, Carol E. Nicholson “A fool is a man who never tried an experiment in his life.” Erasmus Darwin, 1792 Pearls…
Anesthesia Principles and Operating Room Anesthesia Regimens
Chapter 121 Anesthesia Principles and Operating Room Anesthesia Regimens Joseph D. Tobias Intraoperative anesthetic can be provided by one of five techniques, which include local anesthesia (sometimes referred to as…
Congenital Immunodeficiencies
Chapter 92 Congenital Immunodeficiencies M. Teresa de la Morena Pearls • A congenital immunodeficiency should be considered in patients with a family history of immunodeficiency, recurrent or persistent infections, infections…
Gastrointestinal Pharmacology
Chapter 87 Gastrointestinal Pharmacology Louis L. Bystrak, Ann Marie Heine, Kelly A. Michienzi, Sasko D. Stojanovski Pearls • Antiemetic management in both chemotherapy induced nausea and vomiting and postoperative nausea…
