Anticoagulants
Anticoagulants Betty C. Chen and Lewis S. Nelson BACKGROUND Systemic anticoagulation is widely used to treat patients with or at risk for thromboembolic events. Vitamin K antagonists (VKAs) such as…
Controversies in Arrhythmia Management
Controversies in Arrhythmia Management Sam Senturia BACKGROUND Emergency physicians are tasked with managing a wide range of arrhythmias. Rather than reviewing the management of all common arrhythmias, this chapter addresses…
Acute Leukemia
Acute Leukemia Martina Trinkaus ACUTE LEUKEMIA Acute leukemia is a neoplasm of the stem cell that results in rapid accumulation of immature myeloid or lymphoid precursors (functionally inert blasts) in…
Pulmonary Toxins
Pulmonary Toxins Hong K. Kim and Rama B. Rao BACKGROUND The pulmonary system has multiple important physiologic functions. The most essential—oxygenation of hemoglobin—occurs across a layer of endothelial cells in…
High Risk Pulmonary Embolism
High Risk Pulmonary Embolism Tsuyoshi Mitarai BACKGROUND In an autopsy series of hospital deaths, pulmonary embolism (PE) was found in approximately 15% of the cases and—after excluding incidental PE—to be…
Sickle Cell Disease
Sickle Cell Disease Richard Ward BACKGROUND Sickle cell disease (SCD) is one of the most common genetic disorders in North America, affecting an estimated 70,000 individuals. It results from a…
Gastrointestinal Hemorrhage
Gastrointestinal Hemorrhage Parvathi A. Myer and Shai Friedland LOWER GASTROINTESTINAL BLEEDING Background Lower gastrointestinal bleeding (LGIB), defined as bleeding below the ligament of Treitz, accounts for 20% of all acute…
Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome Darryl Abrams and Daniel Brodie BACKGROUND Acute respiratory distress syndrome (ARDS) is characterized by the rapid onset of hypoxemia and bilateral pulmonary infiltrates consistent with pulmonary…
