Metabolic Inhibitors

Dec 22, 2016 by in CRITICAL CARE Comments Off on Metabolic Inhibitors

Metabolic Inhibitors Lauren K. Shawn and Lewis S. Nelson BACKGROUND The complicated metabolic pathways of the human body present multiple opportunities for poisoning. Toxins can inhibit essential pathways in many…

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Pancreatitis

Dec 22, 2016 by in CRITICAL CARE Comments Off on Pancreatitis

Pancreatitis Susan Y. Quan and Walter G. Park BACKGROUND The pancreas is approximately 6 to 10 inches long, is located directly behind the stomach, and has distinct endocrine and exocrine…

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Biomarkers in Sepsis

Dec 22, 2016 by in CRITICAL CARE Comments Off on Biomarkers in Sepsis

Biomarkers in Sepsis David M. Maslove BACKGROUND According to the Biomarkers Definition Working Group, a biomarker is any “…characteristic that is objectively measured and evaluated as an indicator of normal…

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Rhabdomyolysis

Dec 22, 2016 by in CRITICAL CARE Comments Off on Rhabdomyolysis

Rhabdomyolysis Audrey K. Wagner and Deborah M. Stein BACKGROUND Rhabdomyolysis is a syndrome characterized by the necrosis of striated muscle and the subsequent release of intracellular contents—including myoglobin, electrolytes, creatine…

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Palliative Care in the Emergency Department

Dec 22, 2016 by in CRITICAL CARE Comments Off on Palliative Care in the Emergency Department

Palliative Care in the Emergency Department Lawrence A. Ho and J. Randall Curtis BACKGROUND Emergency medicine is typically characterized as a fast-paced, procedure-based specialty that focuses on the evaluation and…

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Adrenal Insufficiency

Dec 22, 2016 by in CRITICAL CARE Comments Off on Adrenal Insufficiency

Adrenal Insufficiency Thomas B. Perera BACKGROUND The adrenal glands are two small, irregularly shaped bodies located superior to each renal pole. Each gland contains two distinct structures, the outer adrenal…

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Cardiotoxins

Dec 22, 2016 by in CRITICAL CARE Comments Off on Cardiotoxins

Cardiotoxins Nicholas J. Connors and Silas W. Smith BACKGROUND Numerous therapeutic options exist for medical management of dysrhythmia, heart failure, and hypertension. In 2011, more than 42.4 million patients received…

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Noninvasive Hemodynamic Monitoring

Dec 22, 2016 by in CRITICAL CARE Comments Off on Noninvasive Hemodynamic Monitoring

Noninvasive Hemodynamic Monitoring Chad M. Meyers BACKGROUND The provision of optimal medical care presents a dilemma in emergency medicine. As the importance of early resuscitation continues to be reinforced, the…

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Heart Failure and Cardiogenic Shock

Dec 22, 2016 by in CRITICAL CARE Comments Off on Heart Failure and Cardiogenic Shock

Heart Failure and Cardiogenic Shock Daniel Sedehi and Venu Menon Background Acute heart failure syndrome (AHFS) is a term intended to capture pathologic changes in cardiac function that are new…

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