Fibrocystic Change: Proliferative Changes
(1) Chennai Breast Centre, Chennai, India The terminal ductal lobular unit is normally 1–2 mm in size but can vary from 1 to 8 mm in size. Around the…
Metaplastic Carcinoma
(1) Chennai Breast Centre, Chennai, India Metaplastic carcinoma is a rare tumor of the breast accounting for <1 % of all breast malignancies. The 2003 WHO publication “Tumours of…
Invasive Papillary Carcinoma
(1) Chennai Breast Centre, Chennai, India Invasive papillary carcinomas account for 1–2 % of all invasive breast carcinomas and tend to occur in postmenopausal women in their mid 60s….
Medullary Cancer of the Breast
(1) Chennai Breast Centre, Chennai, India Medullary carcinoma of the breast accounts for 2–7 % of all invasive breast cancers. They tend to occur more frequently in younger women….
Targeted Therapies
(1) Chennai Breast Centre, Chennai, India The most important advance in targeted therapy for breast cancer is the ability to target the estrogen receptor(ER) and human epidermal growth factor…
Breast MR Imaging
(1) Chennai Breast Centre, Chennai, India Magnetic resonance (MR) imaging of the breast has evolved over the years and is now proven to be a sensitive modality for detection…
Overview of IHC in Breast Lesions
(1) Chennai Breast Centre, Chennai, India A detailed morphological analysis by careful scrutiny of hematoxylin and eosin-stained slides is sufficient to diagnose most breast lesions. However, many lesions defy…
Hormonal Therapy in Nonmetastatic Breast Cancer
(1) Chennai Breast Centre, Chennai, India Adjuvant Hormonal Therapy Introduction Breast cancer is one of the few cancers which are under hormonal regulation, and the manipulation of hormonal control…
Adjuvant/Neoadjuvant Systemic Therapies in Breast Cancer
(1) Chennai Breast Centre, Chennai, India Adjuvant Chemotherapy Introduction Breast cancer is the most common cancer in females in Western countries [1]. The most recent Globocan data shows that…
Breast Pathology: Conventional Prognostic Markers
(1) Chennai Breast Centre, Chennai, India Breast cancer is a heterogeneous disease with a varied clinical outcome, underscoring the need for the use of reliable predictive and prognostic biomarkers….
