Obstetric Anesthesia

Complications in Obstetrics and Obstetric Anesthesia

The Volume of Blood for Epidural Blood Patch in Obstetrics: A Randomized, Blinded Clinical Trial

Paech MJ, Epidural Blood Patch Trial Group (Univ of Western Australia, Crawley, Australia; et al) Anesth Analg 113:126-133, 2011^§

Abstract

Background

Our aim in this multinational, multicenter, randomized, blinded trial was to determine the optimum of 3 volumes of autologous blood for an epidural blood patch.

Methods

Obstetric patients requiring epidural blood patch after unintentional dural puncture during epidural catheter insertion were allocated to receive 15, 20, or 30 mL of blood, stratified for the timing of epidural blood patch and center. Participants were followed for 5 days. The primary study end point was a composite of permanent or partial relief of headache, and secondary end points included permanent relief, partial relief, persisting headache severity, and low back pain during or after the procedure.

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