Chapter 94
Thoracic Surgical Patient
Intraoperative
Critical elements of care during the thoracic procedure include patient positioning, analgesia strategies, ventilator and acid-base management, fluid replacement, and extubation considerations. For most thoracic procedures epidural analgesia, typically placed prior to the induction of general anesthesia, is appropriate. If placement of an epidural catheter is anticipated, the American Society of Regional Anesthesia and Pain Medicine has made specific recommendations regarding anticoagulation surrounding the time of the procedure (Table 94.1). The narcotic sparing effects of epidural analgesia combined with the excellent pain coverage make epidural analgesia optimal for thoracic surgical procedures. When this is not an option, however, intercostal nerve blockade with long-acting local anesthetic agents or placement of extrapleural or paravertebral infusion catheters may be a viable alternative (Chapter 87).
TABLE 94.1
Management of Anticoagulant Agents with Neuraxial Anesthesia
Anticoagulant | Recommended time to withhold prior to neuraxial procedure∗ | If restarting, recommended time to withhold after the neuraxial procedure∗ |
Alteplase (TPA)—full dose for stroke, MI, etc. | 10 days | 10 days |
Aspirin | Does not need to be withheld | Does not need to be withheld |
Clopidogrel | 7 days | 2 hours |
Dabigatran | 7 days | 24 hours (or 6 hours after pulling an epidural catheter until next dose, whichever is later) |
LMWH | 12–24 hours | 6–8 hours (wait 2 hours after pulling an epidural catheter to administer next dose) |
NSAIDs | Do not need to be withheld | Do not need to be withheld |
UF heparin (intravenous) | 2–4 hours | 1 hour (same time for delay in restarting after pulling epidural catheter) |
UF heparin 5000 U q12h (subcutaneous for VTE prophylaxis) | Does not need to be withheld | Does not need to be withheld (wait 2 hours after pulling an epidural catheter until next dose) |
Warfarin | 5 days (INR should be less than 1.5) | 2 hours (wait until INR less than 1.5 before pulling epidural catheter) |
∗Recommendations made by the American Society of Regional Anesthesia and Pain Medicine.
Most thoracic procedures require the institution of single lung ventilation. Careful monitoring of airway pressures during the operation is critical to avoid barotrauma. The relationship between fluid management and barotrauma continues to be an active area of investigation, but barotrauma seems to predispose to capillary leak and the development of postoperative pulmonary edema. This is particularly important during lung resection or pneumonectomy. The development of postpneumonectomy pulmonary edema or acute respiratory distress syndrome (ARDS) in the remaining lung remains a vexing clinical problem that is mitigated by attention to these intraoperative factors.
Postoperative
Initiating Enteral Feeding
Most patients who undergo pulmonary resection can eat the next day or, rarely, the same day of surgery. It is critical, however, to minimize the risk of aspiration. Aspiration is a common occurrence following thoracic surgery, in part related to laryngeal dysfunction resulting from double lumen endotracheal tube placement. One of the most effective methods to minimize aspiration is to ensure the patient is not in the recumbent or semirecumbent position while eating. Formal swallow evaluations have not been found effective when performed routinely on all patients, but informal supervision during the early phase of recovery to detect cough and to emphasize the importance of careful mastication and swallowing is helpful. Thin liquids are usually difficult for patients with a compromised larynx to swallow properly, and thickening agents or delayed introduction of thin liquids should be considered. Patients who have undergone esophageal procedures are at even higher risk of aspiration likely related to neurapraxia and muscle dysfunction from cervical dissection. In these patients, introduction of oral nutrition or medications is typically delayed to permit esophageal anastomoses to heal. Hoarseness, often indicative of recurrent laryngeal nerve dysfunction, can also last for several days because of vocal cord edema.
Fluid and Electrolyte Management
Electrolyte abnormalities are common in the perioperative setting. Hypokalemia should be aggressively corrected to reduce the risk of arrhythmias. Hyperkalemia should typically be treated first with diuretic administration. Hyponatremia, often from syndrome of inappropriate antidiuretic hormone (SIADH), is also common and should be treated with free water restriction, added dietary salt, and attention to other electrolyte abnormalities, particularly potassium (Chapters 39 and 84). Serum sodium concentrations in the 131 to 135 mEq/L range are common and can be managed without aggressive therapy.