G Polycythemia vera
Definition and pathophysiology
Polycythemia vera is a myeloproliferative neoplastic disorder that generally occurs in patients between 60 and 70 years of age. Hyperactivity of myeloid progenitor cells results in increased production of erythrocytes, leukocytes, and platelets.
Laboratory results
Hemoglobin concentrations typically exceed 18 g/dL, and platelet counts can be greater than 400,000/mm3.