Nonopioid Analgesic and Adjunct Drugs



Chemical Structure 9.1
Dexamethasone



A310120_1_En_9_Fig2_HTML.jpg


Chemical Structure 9.2
Dexmedetomidine


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Chemical Structure 9.3
Acetaminophen/paracetamol


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Chemical Structure 9.4
Ketamine


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Chemical Structure 9.5
Ketorolac


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Chemical Structure 9.6
Celecoxib





References



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Jackson LM, Hawkey CJ. COX-2 selective nonsteroidal anti-Inflammatory drugs: do they really offer any advantages? Drugs. 2000;59(6):1207–16. Review.PubMedCrossRef


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Viscusi ER, Frenkl TL, Hartrick CT, Rawal N, Kehlet H, Papanicolaou D, et al. Perioperative use of etoricoxib reduces pain and opioid side-effects after total abdominal hysterectomy: a double-blind, randomized, placebo-controlled phase III study. Curr Med Res Opin. 2012;28(8):1323–35.PubMedCrossRef


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Bing RJ, Lomnicka M. Why do cyclo-oxygenase-2 inhibitors cause cardiovascular events? J Am Coll Cardiol. 2002;39(3):521–2.PubMedCrossRef


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Lin J, Zhang L, Yang H. Perioperative administration of selective cyclooxygenase-2 inhibitors for postoperative pain management in patients after total knee arthroplasty. J Arthroplasty. 2013;28(2):207–13.PubMedCrossRef


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Johnson AG, Seidemann P, Day RO. NSAID-related adverse drug interactions with clinical relevance. An update. Int J Clin Pharmacol Ther. 1994;32(10):509–32.PubMed


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Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids – new mechanisms for old drugs. N Engl J Med. 2005;353:1711–23.PubMedCrossRef


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Romundstad L, Stubhaug A. Glucocorticoids for acute and persistent postoperative neuropathic pain: what is the evidence? Anesthesiology. 2007;107(3):371–3.PubMedCrossRef


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Waldron NH, Jones CA, Gan TJ, Allen TK, Habib AS. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth. 2013;110(2):191–200.PubMedCentralPubMedCrossRef


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Tolver MA, Strandfelt P, Bryld EB, Rosenberg J, Bisgaard T. Randomized clinical trial of dexamethasone versus placebo in laparoscopic inguinal hernia repair. Br J Surg. 2012;99(10):1374–80.PubMedCrossRef


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Lunn TH, Andersen L, Kristensen BB, Husted H, Gaarn-Larsen L, Bandholm T, et al. Effect of high-dose preoperative methylprednisolone on recovery after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial. Br J Anaesth. 2013;110(1):66–73.PubMedCrossRef

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Sep 18, 2016 | Posted by in ANESTHESIA | Comments Off on Nonopioid Analgesic and Adjunct Drugs

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