W18 Lumbar Puncture
Before Procedure
Indications
• The need to obtain cerebrospinal fluid to diagnose other inflammatory or degenerative CNS diseases
Contraindications
• Absolute:
• Intracranial or spinous (especially intramedullary) mass (e.g., tumor, abscess). If there is concern, an imaging study should be performed before the procedure. A rapid decrease in intracranial pressure from withdrawal of CSF could precipitate herniation or worsening of spinal cord function if a mass lesion is present.
• Relative:
• Coagulopathy and/or thrombocytopenia, because an epidural hematoma can develop at the puncture site. Fresh frozen plasma and platelets should be infused to correct hematologic abnormalities before the procedure. If a coagulopathy is discovered after the procedure, therapy should still be given, because bleeding can occur for many hours.
• If a lumbar puncture is being performed to evaluate a patient for aneurysmal subarachnoid hemorrhage, withdraw the smallest possible amount of CSF to obtain the necessary laboratory tests. Reducing the CSF pressure could precipitate rebleeding.
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