Technique
Indications
Contraindications
Side effects
Protocol
Note
High-frequency oscillatory ventilation (HFOV)
Acute respiratory distress syndrome with hypoxemia refractory to conventional protective ventilation
Recent lung surgery, lung disease characterized by airway narrowing or air trapping, intracranial hypertension
Increased mean airway pressures, use of vasoactive drugs, neuromuscular blockers, and sedatives
Initial meanairway pressureof 30 cm H2O,later adjustedto maintainPaO2 55–80 mmHg.HFOV tidal volumesreduced using thehighest frequencyfor maintainingpH >7.25
Increases mortality compared to protective lung ventilation, avoid first-line use
References
1.
2.
Webb H, Tierney D (1974) Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: protection by positive endexpiratory pressure. Am Rev Respir Dis 110:556–565PubMed
3.
Dreyfuss D, Basset G, Soler P, Saumon G (1985) Intermittent positive-pressure hyperventilation with high inflation pressures produces pulmonary microvascular injury in rats. Am Rev Respir Dis 132:880–884PubMed
4.
5.
The Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342(18):1301–1308CrossRef
6.
7.
Villar J, Pérez-Méndez L, Blanco J, Añón JM, Blanch L, Belda J, Santos-Bouza A, Fernández RL, Kacmarek RM, Spanish Initiative for Epidemiology, Stratification, and Therapies for ARDS (SIESTA) Network (2013) A universal definition of ARDS: the PaO2/FiO2 ratio under a standard ventilatory setting–a prospective, multicenter validation study. Intensive Care Med 39(4):583–592CrossRefPubMed