Drug
Indications
Cautions
Side effects
Dose
Notes
Growth hormone
Growth hormone deficiency
Prolonged intensive care unit stay
Diabetes mellitus
Chronic renal failure
Steroids
Critically ill
Appears safe
Water retention
In critically ill patients, it worsen septic shock and multiorgan failure
Hyperglycemia
Up to 8 mg/day (1 IU = 0.33 mg)
It increases mortality in non-deficient critically ill patients
References
1.
Takala J, Ruokonen E, Webster NR et al (1999) Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 341:785–792CrossRefPubMed
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