Pain is a complex multidimensional symptom. It is determined not only by actual or potential tissue injury and normal and abnormal activity of the nervous system, but also by the patient’s personal beliefs, mood, previous painful experiences, psychosocial stressors, coping mechanisms, and motivational factors. Evaluation of a patient with chronic pain should take into consideration all of these factors. Unfortunately, there is no single test or scale that can measure pain comprehensively, reliably, or objectively. A thorough history and physical examination, in combination with other diagnostic tools, are critical in the evaluation of pain patients to identify anatomic and physiologic pain generators. Several visits may be required to elucidate relevant medical and pyschosocial factors. The patient’s motivation for the evaluation must be clarified early (i.e., whether there are issues of litigation or disability affecting the patient’s pain and whether the patient perceives the potential to control pain as coming from within or without). To do this, it is important to listen well, develop the patient’s trust, and not overly structure the interview. Chronic pain patients need validation. Without it, they cannot offer their trust, and trust is vital for treatment compliance and a successful outcome.
Pain assessment is a dynamic process that evolves with the pain management plan. The pain evaluation should be used to localize the source of pain; to determine its quality, pattern, and intensity; to define exacerbating and attenuating factors; and to assess how environmental and behavioral influences affect the pain. Clinicians should always try to make a diagnosis before implementing a treatment plan, recognizing that jumping to a premature conclusion might result in inappropriate treatment or harm to the patient. It is also necessary, at times, to rethink the diagnosis, despite previous and thorough workups. In this chapter, we focus on the history taking and targeted physical examination of a pain patient, pertinent diagnostic testing, pain measurement tools, and models of pain assessment and management.
Pain should be broadly defined as nociceptive (somatic or visceral), neuropathic, or idiopathic. Toward this end, pain location is of utmost importance to accurate diagnosis. It may be well localized, as in entrapment neuropathy (e.g., carpal tunnel syndrome), widespread and diffuse (e.g., fibromyalgia), or regional (e.g., musculoskeletal pain). Patterns of radiation may help determine the site of pathology, such as in cervical or lumbar radiculopathy. Radicular pain (along a dermatome) implies involvement of a nerve root. Pain may also be referred, as in visceral pain, when it is felt over a particular area of skin that is embryologically associated with but anatomically distant from the source of irritation. Accurate characterization of the pain’s location and pathophysiology provides the rationale for treatment. Tables 8-1, 8-2, and 8-3 provide examples of referred pain contrasted with clinical findings associated with nerve root versus peripheral nerve pathology.
Patterns of Referred Pain
Origins of Pain | Region of Pain Referral |
Heart | Chest, left arm, jaw, epigastrium (C8–T8) |
Esophagus | Substernal region |
Diaphragm/liver capsule | Shoulder (C4) |
Kidney | Lower thorax and back (T11–L1) |
Ureter (upper) | Groin, testes, or ovary |
Ureter (terminal) | Scrotum, labia |
Prostate | Lower back (T10–T12) |
Uterus | Lower back (T10–T12) |
Ovary | Anterior thigh |
Upper cervical facets | Occiput, vertex, and toward frontal region of head |
Lower cervical facets | Shoulder, neck, and scapulae |
Lumbar facets | Groin, buttocks, anterior and posterior thighs, calves; can be felt above L5, midline |
Sacroiliac joints | Groin, buttocks, anterior and posterior thighs, calves; should not refer above L5, midline |
Clinical Manifestations of Root Versus Nerve Lesions in the Arm
Roots | C5 | C6 | C7 | C8 | T1 |
Sensory supply | Lateral border of upper arm | Lateral forearm, including finger 1 | Over triceps, midforearm, and finger 3 | Medial forearm to finger 5 | Axilla down to elbow |
Reflex affected | Biceps reflex | None | Triceps reflex | None | None |
Motor loss | Deltoid | Biceps | Latissimus dorsi | Finger extensors | Intrinsic hand muscles (in some thenar muscles through C8) |
| Infraspinatus | Brachialis | Pectoralis major | Finger flexors |
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| Rhomboids | Brachioradialis | Triceps | Flexor carpi ulnaris |
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| Supraspinatus |
| Wrist extensors | Wrist flexors |
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Nerves | Axillary (C5, C6) | Musculocutaneous (C5, C6) | Radial (C5–C8) | Median (C6–C8, T1) | Ulnar (C8, T1) |
Sensory supply | Over deltoid | Lateral forearm to wrist | Lateral dorsal and back of thumb and finger 2 | Lateral palm and lateral fingers 1, 2, 3, and half of 4 | Medial palm and fingers and medial half of finger 4 |
Reflex affected | None | Biceps reflex | Triceps reflex | None | None |
Motor loss | Deltoid | Biceps brachialis | Brachioradialis | Abductor pollicis brevis | Intrinsic hand muscles |
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| Finger extensors | Long flexors of fingers 1, 2, 3 | Flexor carpi ulnaris |
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| Forearm supinator |
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| Triceps | Pronators of forearms | Flexors of fingers 4 and 5 |
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| Wrist extensors | Wrist flexors |
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Clinical Manifestations of Root Versus Nerve Lesions in the Leg
Roots | L2 | L3 | L4 | L5 | S1 |
Sensory supply | Across upper thigh | Across lower thigh | Across knee to medial malleolus | Side of leg to dorsum and sole of foot | Behind lateral malleolus to lateral foot |
Reflex affected | None | None | Patellar reflex | None | Achilles tendon reflex |
Motor loss | Hip flexion | Knee extension | Inversion of foot | Dorsiflexion of toes and foot | Plantar flexion and eversion of foot |
Nerves | Obturator (L2–L4) | Femoral (L2–L4) | Peroneal division of sciatic nerve (L4, L5, S1–S3) | Tibial division of sciatic nerve (L4, L5, S1–S3) |
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Sensory supply | Medial thigh | Anterior thigh to medial malleolus | Anterior leg to dorsum of foot | Posterior leg to sole and lateral aspect of foot |
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Reflex affected | None | Patellar reflex | None | Achilles tendon reflex |
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Motor loss | Adduction of thigh | Extension of knee | Dorsiflexion, inversion, and eversion of foot | Plantar flexion and inversion of foot |
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Detailed history taking at the first visit and a focused history (with emphasis on response to recent intervention) on subsequent visits is extremely beneficial. In many pain centers, the physician obtains a history after reviewing forms (see Appendix B) completed by the patient before the first interview. Some of the important points to be covered in this part of the evaluation are:
Location of pain.
Character of pain.
How and when the pain started.
If the pain is continuous or intermittent.
Exacerbating and relieving factors.
Effect of certain positions and activities on pain.
Effect of stress on the pain.
Effect of alcohol and other substances on pain.
If there is an associated sleep disturbance.
If there is an associated mood disturbance.
Effect of pain on functioning at work or school.
Effect of pain on quality of life, including social, sexual, and family interactions.
Effect of pain treatment on cognitive, social, and sexual function.
Motivation: issues of secondary gain (i.e., disability or psychological attention from partner, parents, or spouse).
If a lawsuit is involved.
If there is anyone the patient blames for the pain.
Beware of attributing new pain to an already defined process. For example, someone with ankylosing spondylitis can still develop a herniated disk, and cancer pain may change or worsen because of disease spread, tolerance to medications, side effects of treatment, or a new psychosocial stressor.
The physical examination starts with the first clinical interaction between the patient and clinician. It begins with how the patient responds to the initial greeting: getting up, walking, sitting down, and posture during these activities. Appearance (general health, weight, muscle bulk, and grooming), attitude and behavior (degree of distress and reactions to specific examination maneuvers), and gait (ataxia, walking with a limp, or requiring a cane or walker) can provide important information. The presence or absence of masses or lesions, signs of injury or trauma, and limb asymmetry regarding skin, hair, nails, or temperature changes should be noted. Alignment of the spine (scoliosis, kyphosis, loss of curvature) and range of motion (ROM) should be noted. Joint shape, swelling, redness, and tenderness should also be noted. Measurement of vital signs may prove useful in evaluating stress, pain (which alters vital signs in young children), and side effects of medication.