Head Injury and Neuroanesthesia

Decompressive Craniectomy and Early Cranioplasty for the Management of Severe Head Injury: A Prospective Multicenter Study on 147 Patients

Chibbaro S, Di Rocco F, Mirone G, et al (Lariboisiére Univ Hosp, Paris, France; Necker Univ Hosp, Paris, France; Naples Univ Hosp, Italy; et al) World Neurosurg 75:558-562, 2011^§

Abstract

Objective

In emergency care of patients with severe blunt head injury, uncontrollable high intracranial pressure is one of major causes of morbidity and mortality. The purpose of this study was to evaluate the efficacy of aggressive surgical treatment in managing uncontrollable elevated intracranial pressure coupled with early skull reconstruction.

Methods

This was a prospective study on a series of 147 consecutive patients, managed according to the same protocol by five different neurosurgical units, for severe head injuries (Glasgow coma scale score ≤8/15 and high intracranial pressure >25 mm Hg) during a five-year period. All patients received a wide decompressive craniectomy and duroplasty in the acute phase, and a cranioplasty was also performed within 12 weeks (median 6 weeks, range 4–12 weeks).

Results

The emergency decompressive surgery was performed within 28 hours (median 16 hours, range 6–28 hours) after sustaining the head injury. The median preoperative Glasgow coma scale score was 6/15 (range 3–8/15). At a mean follow-up of 26 months (range 14–74 months) 14 patients were lost to long-term follow-up, leaving only 133 patients available for the study. The outcome was favorable in 89 (67%, Glasgow outcome score 4 or 5), it was not favorable in 25 (19%, Glasgow outcome score 2 and 3), and 19 patients (14%) died. A younger age (<50 years) and earlier operation (within 9 hours from trauma) had a significant effect on positive outcomes (P < 0.0001 and P < 0.03, respectively).

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