Chapter 32 In the ED, the complaint of constipation should be of concern when it represents a significant change from a patient’s own normal pattern that is creating discomfort for the patient. This change may manifest as a decrease in frequency of defecation, sudden and persistent change in the character or amount of stools (especially decrease in stool caliber), blood in the stool, or problems expelling the stool.1 The prevalence of constipation varies worldwide. In North America the prevalence is approximately 16%.2 In adults, constipation is more common in women, the elderly, those with high body mass index, and those with low socioeconomic status.2 A consistent trend of increasing prevalence of constipation is observed with age, with significant increases after the age of 70 years. The high prevalence among elderly patients is multifactorial and related to a diet low in fiber, sedentary habits, multiple medications, and various disease processes that impair neurologic and motor control. Normally the gastrointestinal tract is presented with 9 to 10 L/day of secretions and ingested fluids. The small intestine usually absorbs all of this except for approximately 500 mL. The colon mixes the ileal effluent, ferments and salvages the unabsorbed carbohydrate residues, and desiccates the contents to form stool. The process of stool transport and evacuation is complex and is regulated by neurotransmitters, intrinsic colonic reflexes, and a multitude of learned and reflex mechanisms that are not fully understood. Constipation may result from structural, metabolic, mechanical, neurologic, or behavioral disorders that affect the colon or anorectum either directly or indirectly.3–5 The causes of constipation are numerous. Causes of constipation can be divided into primary (no apparent external cause) and secondary causes (summarized in Box 32-1). These two groupings have some overlap. In the ED, patients most commonly have acute constipation resulting from side effects of medications or avoidance of defecation secondary to presence of painful perianal lesions such as fissures, hemorrhoids, or perirectal abscesses. A thorough, detailed history usually identifies the most likely cause of the patient’s constipation. Defining what the patient means by “constipation” is a good starting point. Essential information includes the presence or absence of signs or symptoms that the American College of Gastroenterology terms “alarm symptoms.” These include fever, anorexia, nausea, vomiting, blood in the stool, anemia, weight loss of more than 10 lb, a family history of colon cancer, onset of constipation after the age of 50, and acute onset of constipation in an elderly patient.1
Constipation
Perspective
Epidemiology
Pathophysiology
Diagnostic Approach
Pivotal Findings
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Constipation
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