Chapter 99 Children in the Wilderness
Once the realm of a few adventurous individuals, the wilderness today attracts an ever-broader range of explorers. This includes many in the pediatric age group, as parents seek to share the joys and lessons of wilderness travel with their children. In 2008, of the more than 60 million people participating in backpacking and camping, nearly 25% were younger than 17 years.57 Millions of other children annually visit national parks and recreation areas.
What Makes Children Different?
Size and Shape
Children are distinct from adults in a variety of physical, physiologic, and psychological ways. The most obvious difference is size. During development, children may grow from the average 7-lb (3.18-kg) baby to a 140-lb (63.5-kg) adolescent, a 20-fold difference. Accordingly, medications and fluids must be calculated on an individual basis, based on the weight of the child. Table 99-1 lists average weights for age.
Age | Weight | |
---|---|---|
yr | kg | lb |
1 | 10 | 22 |
3 | 15 | 33 |
6 | 20 | 44 |
8 | 25 | 55 |
9 | 30 | 66 |
11 | 35 | 77 |
13 | 45 | 100 |
From U.S. Centers for Disease Control and Prevention National Center for Health Statistics (http://www.cdc.gov/nchs/).
Children are not only smaller than adults, they also have a larger surface-area-to-mass ratio. For example, a 7-lb (3.18-kg) infant has 2.5 times more body surface area per unit weight than a 140-lb (63.5-kg) adult. Not only is the surface area of the young child’s body larger, the head, which is the part of the body most often left exposed, also takes up a larger proportion of the body (Figure 99-1). As a result, children experience greater exposure to environmental factors, such as cold, heat, and solar radiation. They are also more likely to suffer toxic effects from topical agents, such as medications.
Musculoskeletal System
Another key difference between the musculoskeletal systems of children and adults is that children have an open growth plate, or physis, at the ends of long bones. The physis connects the metaphysis to the epiphysis and consists of soft cartilaginous cells that have the consistency of rubber and act as shock absorbers (Figure 99-2). They protect the joint surfaces from suffering the grossly comminuted fractures seen in adults. However, because the growth plate is more vulnerable to injury than are the strong ligaments or capsular tissues that attach to the epiphysis, a true sprain in a child is rare. Any significant juxta-articular tenderness in a child should be assumed to be a growth plate injury and immobilized accordingly. Such an injury is most common at the ankle (lateral malleolus), knee (distal femur), and wrist (distal radius). Physeal fractures have been classified into five Salter–Harris groups (see Figure 99-2). Salter–Harris I and II fractures generally heal without complications. Salter–Harris III and IV fractures often require open reduction of displaced fractures to realign the joint and growth plates and to permit normal growth. A Salter–Harris V fracture has a poor prognosis; impaction and crushing of some or all of the growth plate may result in a bony bridge that inhibits further growth or causes unequal, angulated growth. Consequently, any significant injury, especially if it involves the growth plate, requires full evaluation in a medical facility.
Cardiovascular and Respiratory Systems
Basic physiologic parameters change greatly during the transitions from infancy to childhood to adulthood. Recognizing these differences is important to avoid unnecessary and potentially harmful interventions in healthy children, and to intervene aggressively when abnormal vital signs are truly present. For example, a blood pressure of 70/35 mm Hg, pulse rate of 160 beats/min, and respiratory rate of 50 breaths/min are considered ominous vital signs for an adult. However, these vital signs are normal in a 2-month-old infant. Although blood pressure readings may not be available in a wilderness setting, it is possible to assess the general appearance, work of breathing, respiratory rate, pulse, and peripheral circulation of an ill child. These observations can accurately predict how sick a child is. In general, infants and children have higher respiratory and heart rates and lower blood pressure than do adults. The normal values for various age groups are presented in Table 99-2. It is important to note that children can often maintain normal blood pressure in the face of significant fluid or blood losses. Once blood pressure drops, however, children can deteriorate very rapidly. Therefore, prompt and aggressive fluid resuscitation is essential when other signs of dehydration or volume loss (e.g., tachycardia, increased capillary refill time, cool extremities) are present.
Age | Heart Rate (beats/min) | Respiratory Rate (breaths/min) |
---|---|---|
0-5 mo | 140 ± 40 | 40 ± 12 |
6-11 mo | 135 ± 30 | 30 ± 10 |
1-2 yr | 120 ± 30 | 25 ± 8 |
3-4 yr | 110 ± 30 | 20 ± 6 |
5-7 yr | 100 ± 20 | 16 ± 5 |
8-11 yr | 90 ± 30 | 16 ± 4 |
12-15 yr | 80 ± 20 | 16 ± 3 |
Thermoregulation
Because environmental extremes are often encountered when traveling in wilderness areas, it is important to recognize that thermoregulation is less efficient in children than in adults. A number of physiologic and morphologic differences make children more susceptible than adults to heat illness. During exercise, children generate more metabolic heat per unit mass than do adults. Children also have lower cardiac output at a given metabolic rate, resulting in lower capacity to convey heat from the body core to the periphery. Because they have a larger surface area–to-mass ratio, children also gain heat more rapidly from the environment than do adults when ambient temperature exceeds skin temperature. In hot environments, cooling from conduction, convection, and radiation ceases to be effective, leaving evaporation (sweating) as the only effective means of heat dissipation. Unfortunately, children have a lower capacity for evaporative cooling, presumably because of decreased sweat volume, regional differences in sweat patterns, and a higher sweat point (the rectal temperature when sweating starts).42 Finally, children acclimatize to hot environments at a slower rate than do adults.
Children are also at greater risk for hypothermia. Their larger surface area–to-mass ratio causes them to cool more rapidly than adults in cold environments. Children also have less subcutaneous fat and, therefore, less body insulation. Infants, in particular, have an inefficient shivering mechanism. This makes them particularly vulnerable to cold environments because shivering is the primary means of generating extra heat when humans are cold.4 In general, humans are poorly adapted for cold environments and must rely on adaptive behavioral responses, such as seeking shelter and dressing appropriately, to maintain body heat. Infants and young children are not capable of these responses and must rely on caregivers to provide shelter and appropriate clothing.
Trauma
Blunt trauma is the leading cause of morbidity and mortality in children ages 1 to 18 years. Closed head injuries are responsible for 80% of pediatric trauma deaths.44 Although pedestrian and motor vehicle accidents are the source of many of these injuries, falls and drowning are close behind. Children differ from adults in their susceptibility to injuries from blunt trauma, and the injuries themselves differ. By nature of their smaller size, children’s airways are more prone to obstruction, particularly by their relatively large tongues. Their rib cages are more pliable and hence provide less protection to the lungs and mediastinum. Similarly, the abdominal musculature in children is underdeveloped relative to adults, leaving the intra-abdominal organs more vulnerable to injury. Pelvic fractures are uncommon in children; when they do occur, they rarely result in life-threatening bleeding or genitourinary injury.
General Considerations and Expectations
Children of different ages have different needs and abilities. Expectations regarding distances of travel, pace, and safety issues vary depending on age (Table 99-3). This section explores the key issues regarding wilderness travel with children of various ages and provides general expectations for each age group. A number of helpful books that discuss different aspects of wilderness activities with children are listed under Suggested Readings.
Age | Expectation | Safety Issues |
---|---|---|
0-2 yr | Distance traveled depends on adults. Use child carriers | Provide “safe play area” (e.g., tent floor, extra tarp laid out), bells on shoes |
2-4 yr | Difficult age; stop every 15 min, hike 1-2 miles on own | Dress in bright colors, teach how to use whistle |
5-7 yr | Hike 1-3 hr/day, cover 3-4 miles over easy terrain, rest every 30-45 min | Carry whistle (three blows for “I’m lost”), carry own pack with mini first-aid kid and water |
8-9 yr | Hike a full day with easy pace, cover 6-7 miles over variable terrain; if 1.2 m (>4 feet) tall, can use framed pack | As for 5-7 yr, plus teach map use and route finding, precondition by increasing maximal distances by <10%/wk, watch for overuse injuries, keep weight of pack <20% of bodyweight |
10-12 yr | Hike a full day at moderate pace, cover 8-10 miles over variable terrain | As for 8-9 yr; expand route planning role, compass use |
Teens | Hike 8-12 miles or more at adult pace; may see a decrease in pace or distance with growth spurt | As for 10-12 yr, but expand survival and wilderness first-aid knowledge. |
First 2 Years
Equipment
Because infants and young children are not capable of extended hikes, they are typically transported in carriers. Most front carriers work well from infancy until an age when babies can sit fairly well, typically 6 to 9 months (Figure 99-3). It is important that a front carrier extend up high enough in the back to completely support a young baby’s head. Once a child is sitting well, back carriers are better (Figure 99-4). Back carriers function on the same principle as framed backpacks, redistributing the weight off the shoulders and onto the hips. Many back carriers are able to stand alone and can double as a highchair. Children must be strapped into back carriers, because it is easy for a child to be catapulted out of a carrier if the adult bends over or falls.
2 to 4 Years
Safety
When selecting campsites, dangerous features, such as steep drop-offs and fast, deep water, should be avoided. Children should be dressed in brightly colored clothing, so they are more easily located if they become lost (Figure 99-5). As children get older, they may carry a whistle to call for help when they are lost. The standard distress signal is three blows to indicate “I’m lost” or “I need help”; the response is two blows to indicate “help is coming.” Parents should teach children to stay put once they discover they are lost and wait to let help come to them. If children panic and start running when they realize they are lost, they increase the chance not only of getting injured but also of traveling farther from the family. The concept of “hug a tree” will be described later in the chapter.
School Age (5 Years and Up)
Travel Expectations
When parents are planning hiking trips, it is important that they have appropriate expectations for children’s evolving abilities (see Table 99-3). Children enrolled in organized sports activities are likely to have greater endurance in the wilderness. A child’s hiking ability can be estimated by walks around the neighborhood or in a local park. If this practice becomes a routine, children become preconditioned, increase their endurance, and learn to pace themselves. More importantly, parents can learn what to expect and can test methods for motivating their children. It is better to underestimate than to overestimate a child’s ability. Parents should also remember that children, like adults, have good and bad days, so allowances should be made.
Environmental Illnesses
Dehydration
Symptoms
As little as a 2% decrease in bodyweight through fluid loss results in mildly increased heart rate, elevated body temperature, and decreased plasma volume. Water losses of 4% to 5% of bodyweight reduce muscular work capacity by 20% to 30%.42 Symptoms of dehydration include weakness, fatigue, nausea, vomiting, and, ultimately, lethargy. In a young child, the first sign may be irritability and loss of appetite. Dehydration also predisposes a child to other environmental hazards, such as hypothermia, hyperthermia, and acute mountain sickness.
Treatment
It is the caregiver’s responsibility to provide fluids and coax the child to drink frequently. For short (<2-hour) periods of activity, water is as efficacious a rehydration solution as are carbohydrate-electrolyte drinks.42 That being said, a small amount of juice or other sweetener diluted in a larger volume of water will often enhance the fluid intake of a child. Avoid undiluted juices or heavily sweetened drinks because they can worsen dehydration; the high carbohydrate load in these drinks promote an osmotic diuresis. A child eating a normal diet does not require electrolyte replacement unless sweating is prolonged or excessive. By closely monitoring a child’s urine output, fluid deficits can be recognized and promptly managed. A child with decreased urine output or dark, concentrated urine needs extra fluids.
Hypothermia
Children cool more rapidly than do adults because they have a relatively large surface area and often lack the knowledge and judgment to initiate behaviors that maintain warmth in a cold environment (see Chapter 5). In addition, they have a more difficult time, physiologically, maintaining body temperature in cold climates, predominantly because they do not shiver as effectively.4 As a result, parents participating in cold weather recreation with children should be able to recognize, treat, and preferably prevent hypothermia and frostbite.
Hypothermia is defined as core body temperature below 35° C (95° F). At this temperature, the body no longer generates enough heat to maintain body functions. The condition is considered mild when the core temperature is 33° to 35° C (91° to 95° F); moderate at temperatures between 28° and 32° C (82° and 90° F), and severe when it is less than 28° C (82° F). The signs and symptoms of hypothermia are listed in Table 99-4, although these may be quite variable. The most important clue to significant hypothermia is altered mental status. An infant may become lethargic and difficult to arouse. An older child may be shivering, stumbling, or appear confused. These signs merit prompt treatment for hypothermia. Of note, the presence or absence of shivering is not a reliable marker of the severity of hypothermia. Physicians should also caution parents that hypothermia can develop at moderate ambient temperatures if adverse climatic conditions are compounded by illness, fatigue, dehydration, inadequate nutrition, or wet clothing.
Rectal Temperature | Signs and Symptoms | |
---|---|---|
Mild | 33°-35° C | Sensation of cold, shivering, increased heart rate, progressive incoordination in hand movements, developing poor judgment |
(91°-95° F) | ||
Moderate | 28°-32° C | Loss of shivering, difficulty walking or following commands, paradoxical undressing, increasing confusion, decreased arrhythmia threshold |
(82°-90° F) | ||
Severe | <28° C | Rigid muscles, progressive loss of reflexes and voluntary motion, hypotension, bradycardia, hypoventilation, dilated pupils, increasing risk of fatal arrhythmias, appearance of death |
(<82° F) |
Prevention
When preparing for cold weather activities, children should dress in layers to allow clothing to be added or subtracted as necessary (Figure 99-6). This avoids excessive perspiration while maintaining warmth. An inner, wicking layer should be followed by a middle, insulating layer and, finally, by an outer, protective layer.
Because children generally avail themselves of any opportunity to get wet, clothing that maintains low thermal conductance when moist is particularly important. Conductive heat loss may increase fivefold in wet clothing and up to 25-fold if the child is completely immersed in water. Traditional wool retains warmth when wet because of its unique ability to suspend water vapor within the fibers; however, it is heavier than synthetics and takes much longer to dry. Cotton has a high thermal conductance that increases greatly when wet and is, therefore, a poor choice for wilderness activities in cold weather. Synthetic materials (polypropylene, Capilene, Thermax, Coolmax) wick moisture away from the skin and dry quickly, making them ideal for an inner layer. Finely woven merino wool also provides these same advantages as a wicking layer. The middle, insulating layer may incorporate wool, polyester pile or fleece, down, or similar materials. Finally, windproof and water-resistant outer garments (e.g., Gore-Tex) decrease heat loss from convection and keep children dry. Hats and mittens are also essential; the uncovered head of a child dissipates up to 70% of total body heat production at an ambient temperature of 5° C (41° F).4
Frostbite
Localized cold injury can result in frostbite (see Chapter 8). Predisposing factors include wet skin, constricting garments that hinder blood circulation, fatigue, dehydration, contact with cold surfaces, and wind. If skin temperature drops below 10° C (50° F), cutaneous sensation is generally abolished and injury may go unnoticed. Skin cooled to −4° C (25° F) freezes.
Frostbite has traditionally been divided into degrees of injury, much like burns. Determination of depth of injury should occur 24 to 48 hours after rewarming; prior to this, frostbitten skin generally appears hard and feels numb. Skin with superficial frostbite is typically swollen, pink or erythematous, painful, somewhat warm, and often blistered. Sites with deep frostbite are cooler, not edematous, pale, anesthetic, and do not have blisters or bullae. In children, frostbite that extends into bone may affect the growth plate and result in skeletal deformities.4 Verbal children will frequently report cold hands and feet, but adults should be vigilant about checking the extremities and noses/ears of nonverbal children, particularly those poorly visible in back carriers. A mirror, frequently used, can assist in this regard. Reports of small children developing frostbite and hypothermia while being carried on the backs of adults engaged in outdoor winter pursuits are not infrequent.
Hyperthermia
Families participating in wilderness activities in hot climates must take special precautions to avoid heat illnesses (see Chapters 10 and 11). Children do not tolerate the demands of exercise in the heat as well as adults. They generate more heat per kilogram and are less able to disperse heat from the core to the periphery. Parents planning wilderness ventures with children in hot climates can follow some simple guidelines for avoiding heat illness. The most obvious entails reducing the duration and intensity of activities under conditions of high climatic heat stress. The likelihood of heat illness depends on relative humidity, wind velocity, and radiant heat, as well as standard dry-bulb thermometer temperature. Figure 99-7 gives a rough guide for activity levels based on temperature and relative humidity.
Prevention
Children should be fully hydrated before prolonged exercise and actively encouraged to drink fluids at regular intervals.42 Infants and neonates are most vulnerable to heat illness. Under high climatic heat stress, infants fed undiluted cow’s milk or formula may develop marked salt retention and dehydration. They should be given extra water or dilute feedings. The lower osmolar load of breast milk appears to protect against heat illness and hypernatremia.
Sun Damage
Hazards of overexposure to sunlight include sunburn, photoaging, skin cancer, and phototoxic and photoallergic reactions (see Chapter 14). Climatic changes such as global warming and ozone degradation have increased these hazards.54 Preventing ultraviolet damage to skin should begin in childhood, as 50% to 80% of a person’s lifetime sun exposure occurs before 21 years of age.25,48 Adolescence is the period when children are most at risk. In one study, 83% of children 12 to 18 years old reported at least one sunburn per summer; 36% reported three or more sunburns per summer.25 Recent evidence suggests that the risk of developing malignant melanoma increases significantly with the number of sunburns in childhood.19 This risk is even higher if a child is light-skinned with a propensity to burn rather than tan. Tolerance to sun exposure is determined by the amount of melanin in skin and ability of skin to produce melanin in response to sunlight. In general, children have lower melanin levels and thinner skin than do adults and are, therefore, at greater risk of sun damage.
The harmful effects of ultraviolet radiation from the sun can be reduced if parents are educated regarding the dangers of sun exposure and encouraged to use sun-protective clothing and sunscreens early in their children’s lives. One study demonstrated 60% reduction in childhood sunburns with good parental role-modeling and sunscreen vigilance.48 Regular use of sunscreen with sun protection factor (SPF) of at least 15 for the first 18 years of life reduces a person’s lifetime risk of developing nonmelanoma skin cancer by 78%.27
Prevention
The most effective means of preventing sun damage is use of protective clothing and avoidance of excessive sun exposure. Midday hours, particularly around highly reflective surfaces (e.g., water, sand, snow), at high altitude and at the equator are the most dangerous in terms of quantity of ultraviolet exposure. Shady areas should be used for activities during these times. Hats with wide brims and neck drapes help to protect the face and neck from sun exposure (Figure 99-8). Clothing made from tightly woven fabrics is more protective than is clothing made from loosely woven fabric. For example, loosely woven fabrics, such as those used in most T-shirts, have an SPF of only 5. Most clothing loses more of its sun protective effect when wet. Several manufacturers are marketing high-SPF (25 to 50) protective clothing (http://www.coolibar.com; http://www.sunprotectiveclothing.com). This specialized clothing is cool and lightweight, dries quickly, and can maintain its full SPF capabilities when wet (Figure 99-8). Caution is advised on overcast days, because 80% of the sun’s rays still reach the earth even when the sun is not visible.27 In addition, because clouds filter out heat from infrared rays, children feel more comfortable and tend to stay out longer, therefore increasing their overall UV exposure.
FIGURE 99-8 Child with appropriate sun wear: protective clothing, wide-brimmed hat, and sunglasses.
(Courtesy Judith R. Klein, MD.)
Proper eye protection is often overlooked in infants and young children. Excessive ultraviolet light, particularly during snow and water activities, can result in ultraviolet keratitis (see Chapter 28) with even brief exposures. Properly fitting sunglasses that transmit less than 10% of ultraviolet rays should be part of a child’s outdoor activity armamentarium (Figure 99-8). Side shields and polarizing lenses are particularly important in snow conditions.
Sunscreens
Sunscreens formulated with a variety of different agents to prevent UV damage to the skin include physical blocks, chemical blocks, and antioxidants. Physical blocks, such as zinc oxide and titanium dioxide, reflect ultraviolet light and do not penetrate the skin. Chemical blocks prevent ultraviolet light from entering skin, and are themselves absorbed into skin. Chemical blocks have ingredients that block UVB, UVA, or both. Agents that block UVB include PABA, cinnamates, salicylates, and anthranilates; those that block less potent UVA rays include avobenzone and the anthranilates. Benzophenones, oxybenzone, and the physical blocking agents protect against both UVA and UVB.27 Antioxidants present in sunscreens include Vitamins C and E, resveratrol, and pomegranate. These agents help to repair skin damage. Sunscreens that combine protective ingredients with antioxidants are the most effective. The sun protection factor (SPF) is a measure of a sunscreen’s effectiveness. It is measured in terms of the minimal dose (in length of time) of UV radiation required to cause skin erythema. Sunscreens with SPF 30 or higher provide a superior degree of photoprotection and almost completely prevent cellular changes seen with sunburn.27
Overall, there is little difference between child and adult sunscreens except for price. Parents should select sunscreens based on ingredients. Physical blocks are preferred for children because they are difficult to wash/rub off and do not degrade in the sun. Therefore, they do not need to be reapplied with as great frequency as do chemical sunscreens. Zinc oxide can be quite colorful, whereas titanium dioxide is colorless. Apply a thick coat of sunscreen at least half an hour before outdoor activity. Sunscreens must be applied in adequate quantity to provide the SPF indicated on the bottle.51 Select a sunscreen with an SPF of at least 15, but preferably greater than 30. Waterproof sunscreens are preferred if children are anywhere near water, because these products maintain efficacy for up to 80 minutes of water immersion. Sunscreens should be reapplied at least every 2 hours (or more frequently) during prolonged water immersion or excessive sweating. Cream and lotion sunscreens provide superior coverage to spray-on formulations because they can be applied evenly and in the quantities required to provide effective sun protection. Infants younger than age 6 months should be outfitted with hats and protective clothing and should placed in the shade. Sunscreens in this age group should be limited to small areas of skin only, because infant skin is thin and chemically sensitive.
Drowning
According to the Centers for Disease Control, drowning (see Chapter 75) is the number two cause of injury-related death in children, resulting in more than 900 fatalities in children under 14 in 2005.66 Of all deaths among children age 1 to 4 years in 2005, 30% were the result of drowning.66 Those most at risk are unsupervised toddlers and male teenagers, in particular, those with inadequate swimming skills and poor judgment. Morbidity and mortality result from asphyxiation, hypothermia, and/or trauma.
High-Altitude Illness
High-altitude illness (see Chapter 1) can be viewed as a continuum from acute mountain sickness (AMS) to life-threatening conditions such as high-altitude pulmonary edema (HAPE) and high-altitude cerebral edema (HACE). AMS usually develops within 24 hours of ascent. The incidence and severity of AMS depend on individual susceptibility, as well as rate of ascent and altitude attained. In one study, 37% of children who ascended rapidly to 3500 m (11,500 feet) developed AMS.6 Other studies have shown even higher incidences of AMS in children and have suggested that children are more susceptible to hypobaric hypoxia than are adults.43
Prevention
The safest and most effective method of preventing high-altitude illness is to allow for acclimatization via graded ascent. No precise, scientifically proved guidelines exist, given the markedly variable individual susceptibility to altitude illness. However, general recommendations for children (and adults) without altitude experience are listed in Box 99-1. After day trips to higher altitude, children should return to lower altitude to sleep in order to aid acclimatization. The sleeping altitude is particularly important with regard to development of symptoms. A high-carbohydrate diet and plenty of fluids can also help to reduce the risk of high-altitude illness.
BOX 99-1 Preventing High-Altitude Illness
Acetazolamide has been convincingly shown to reduce the incidence of AMS in adults.20 Pretreatment with this agent mimics the acclimatized state by inducing hyperchloremic metabolic acidosis, allowing for a compensatory increase in respiration. There are no published studies of its efficacy in children, but clinical experience suggests that it is beneficial. The primary indication for acetazolamide prophylaxis in children is a history of recurrent AMS despite graded ascent.43 Acetazolamide is given at 5 mg/kg/day, in two divided doses, up to a maximum daily dosage of 250 mg. It should be started 24 hours before ascent and continued for 3 to 5 days while at maximal altitude. It can be discontinued once descent has begun. Side effects include nausea, mild somnolence, and paresthesias that can be particularly bothersome in children. Dexamethasone also prevents or reduces symptoms of AMS in adults, but its use is discouraged in the prevention of AMS in children, because it masks early symptoms of mountain sickness and thereby encourages continued ascent. Ginkgo biloba has also been studied recently as an herbal alternative to acetazolamide for the prevention of AMS; unfortunately, its efficacy is uncertain because of variability in commercially available gingko formulations.36 Salmeterol, an inhaled long-acting β-agonist, has also been studied as a prophylactic agent against HAPE in adults, but it has not been evaluated in children.
Treatment
Treatment of mild AMS requires prompt recognition of symptoms, cessation of ascent, and allowance of time for acclimatization to occur. Proceeding to higher altitude in the presence of symptoms is strongly contraindicated and may lead to the life-threatening conditions HAPE and HACE. Symptomatic therapy includes rest, acetaminophen for headache, and adequate hydration. Promethazine (Phenergan) or ondansetron (Zofran) may be used to relieve nausea and vomiting. Dystonia in response to phenothiazines, such as promethazine, occurs disproportionately in young children, so ondansetron is preferred. Promethazine is given at 0.2 to 0.5 mg/kg/dose up to 25 mg every 6 hours, preferably per rectum; ondansetron is given orally at 0.1 to 0.15 mg/kg up to 4 mg every 4 hours. If symptoms resolve, the child may continue to ascend slowly. However, if symptoms progress or fail to improve, descent is mandatory. Although descent should proceed as far as necessary for improvement, 500 to 1000 m (1600 to 3200 feet) is often sufficient. If immediate descent is not possible, oxygen should be administered if available. Studies examining dexamethasone and acetazolamide for treatment of AMS suggest that both are effective.20 Dexamethasone should be reserved for patients with severe AMS or HACE. The symptoms of HACE or HAPE demand immediate descent and possible evacuation.
Bites and Stings
Bites and stings occur commonly in the pediatric age group. In 2008, the American Association of Poison Control Centers reported that more than 25,000, or roughly one-third, of reported bites and stings occurred in individuals under the age of 20 years.8 Remarkably, no fatalities were reported in this age group. This emphasizes the need for appropriate triage to determine which children require aggressive therapy so that potentially harmful field interventions can be avoided.
Snakes
Of the 8000 venomous snakebites that are estimated to occur in the United States each year, about 20% occur in people under the age of 20 years.8 Although mortality from domestic snakebites is uncommon, about 20% of snakebite-related deaths typically occur in children under the age of 5 years. More than two-thirds of bites in children are on the lower extremities; these are predominantly in younger children walking or running over rocks and in brush. Most snakebites can be prevented. Children should be instructed not to handle snakes, not to reach blindly into crevices, and to avoid turning over rocks and fallen limbs. A useful adage is that hands and feet should never go where the eyes cannot see. When walking through endemic areas, hikers should stay on trails and wear long, loose pants, and boots that extend above the ankle. Campsites should be on open ground, away from wood piles or rock piles.
If a bite occurs, the child should back well away from the snake and be calmed. Agitation and movement of the bitten extremity promote venom circulation. The wound should be cleansed rapidly and any constricting items of clothing or jewelry removed. The bitten extremity should be immobilized promptly and positioned at the level of the heart. No incision over the bite should be made. The use of mechanical suction (e.g., Sawyer extractor) is ineffective at removing snakebite venom and can worsen tissue ischemia in the 99% of endemic snakebites that are inflicted by members of the crotalid family (rattlesnakes, cottonmouths, copperheads).1 Advanced techniques for potentially limiting venom spread, particularly with exotic snake envenomations, are discussed in detail in Chapters 54 and 55. All victims of potentially poisonous snakebites should be transported to a medical facility for prompt evaluation, local wound care, and possible antivenom administration. Crotalidae Polyvalent Immune Fab antivenom (CroFab, Protherics Inc.) has been shown to be safe and effective in children, particularly if administered early.28