Cardiothoracic and Vascular Anesthesia
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol – a clinical trial
Kottenberg E, Thielmann M, Bergmann L, et al (Universitätsklinikum Essen, Germany) Acta Anaesthesiol Scand 56:30-38, 2012§
Evidence Ranking
• A
Expert Rating
• 2
Abstract
Methods
In a randomized, single-blinded, placebo-controlled prospective study, serum troponin I concentration (cTnI) (baseline, and 1, 6, 12, 24, 48, and 72 h postoperatively) were measured during isoflurane/sufentanil or propofol/sufentanil anesthesia with or without RIPC (three 5-min periods of intermittent left upper arm ischemia with 5 min reperfusion each) in non-diabetic patients (n = 72) with three-vessel coronary artery disease (ClinicalTrials.gov(http://ClinicalTrials.gov)NCT01406678).
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