Cardiothoracic and Vascular Anesthesia

Association Between Postoperative Acute Kidney Injury and Duration of Cardiopulmonary Bypass: A Meta-Analysis

Kumar AB, Suneja M, Bayman EO, et al (Univ of Iowa Hosps and Clinics) J Cardiothorac Vasc Anesth 26:64-69, 2012^§

Abstract

Objective

This meta-analysis examined the association between cardiopulmonary bypass (CPB) time and acute kidney injury (AKI).

Design

Meta-analysis of previously published studies.

Setting

Each single-center study was conducted in a surgical intensive care unit and/or academic or university hospital.

Participants

Adult patients undergoing heart surgery with CPB.

Interventions

A systematic literature review was conducted using PubMed, EMBASE, and Cochrane Library databases and Google Scholar from January 1980 through September 2009. Initial search results were refined to include human subjects, age >18 years, randomized controlled trials, and prospective and retrospective cohort studies, meet the Acute Kidney Injury Network definition of renal failure, and report times on CPB.

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