Pain Management

Chronic Pain Management

Increased adolescent opioid use and complications reported to a poison control center following the 2000 JCAHO pain initiative

Tormoehlen LM, Mowry JB, Bodle JD, et al (Indiana Univ School of Medicine, Indianapolis; Indiana Poison Ctr, Indianapolis) Clin Toxicol 49:492-498, 2011^§

Abstract

Context

Adolescents are at risk to abuse opioid analgesics for many reasons, including inaccurate perception of risk and increased drug availability. In 2000, the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) released pain management standards that emphasized pain control as a patient rights issue. This focus on analgesia may have increased both the prescribing and use of opioid analgesics, thereby increasing availability.

Objective

Using data from a US poison center, this study aims to compare the number of adolescent opioid cases and their outcome severity before and after the 2000 JCAHO pain initiative.

Methods

Retrospective case series of opioid exposures involving persons 12–18 years of age reported to a US poison center from 1994 to 2007. The main outcome measure was the number of adolescent opioid cases reported for 1994–2000 compared to 2001–2007. Secondary outcomes included outcome severity, number of cases involving specific opioids, and correlation between the number of cases and the amount of opioids distributed to the state.

Results

There were 1634 adolescent opioid-related cases with 187 cases developing medical complications. Compared with 1994–2000, the rate ratio of cases involving adolescents and opioid analgesics for the years 2001–2007 was 1.69 (95% CI: 1.53, 1.86), and these cases were 2.84 (95% CI: 2.06, 3.91) times more likely to have had medical complications. Medical complications involving methadone (p = 0.001) increased after the JCAHO initiative, while complications related to codeine (p = 0.001) and propoxyphene (p = 0.030) decreased. There were 15 deaths in 2001–2007 and none in 1994–2000 (p = 0.012). Lastly, there was a correlation between the rate of adolescent opioid cases and the amount of opioids distributed to the state (r² = 0.90; p < 0.001).

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