Autosomal dominant inherited syndrome with hydrocephalus, cleft palate, joint contractures, and abnormal dermal ridge patterning of palms and fingertips.

Aase-Smith Syndrome I; Distal Arthrogryposis Type IIB Syndrome; Sheldon-Hall Syndrome.

First described in 1968, in a father and his two children (a stillborn boy and a girl who died at 6 weeks of age), by the American pediatricians Jon Morton Aase and David Weyhe Smith.

Unknown, but extremely rare.

Autosomal dominant.